Research on the Action Mechanism of Antibacterial Chinese Medicine Based on SPR Sensing Technology

Abstract

A detection method based on SPR sensor is proposed to detect the interaction between antimicrobial agents and cytokines and receptors. A bimetallic optical fiber SPR biosensor was fabricated by double layer metal film by vacuum thermal evaporation. The mechanism of Chinese medicine was detected by direct method. The sensor has the function of rapid, objective, accurate and efficient detection of the mechanism of action of Chinese medicine, and the corresponding data are obtained. The application of optical fiber SPR biosensor makes the detection of the mechanism of action of traditional Chinese medicine have the advantages of real-time and high efficiency. It is expected to make new breakthroughs in the study of the target and molecular mechanism of the antibacterial effect of traditional Chinese medicine. Introduction